肖春生

教育和工作经历

2002-2006，中国科学技术大学，高分子科学与工程专业，本科

2006-2012，中国科学院长春应用化学研究所，高分子化学与物理专业，博士

2012-2014，中国科学院长春应用化学研究所，中科院生态环境高分子材料重点实验室，助理研究员

2014-2020，中国科学院长春应用化学研究所，中科院生态环境高分子材料重点实验室，副研究员

2020-2022，中国科学院长春应用化学研究所，中科院生态环境高分子材料重点实验室，项目研究员

2022-至今，中国科学院长春应用化学研究所，中科院生态环境高分子材料重点实验室，研究员

主要荣誉

2017，中国科学院青年创新促进会会员

2022，国家自然科学基金委优秀青年科学基金

研究领域

主要从事生物医用高分子材料的设计、制备及其在生物医学领域的应用。研究组围绕疾病的精准诊断和治疗，开展高分子纳米药物、抗菌高分子材料、医用水凝胶和生物成像分析等相关研究。迄今在Adv. Mater., Adv. Funct. Mater., Small, Biomaterials, Anal. Chem.等国际主流期刊上发表一作/通讯作者论文80余篇。以第一发明人身份，申请国家发明专利17项，其中已获授权14项。作为项目负责人，主持国家自然科学基金4项，主持吉林省优秀青年人才基金项目和重点研发项目各1项。受邀请担任Scientific Reports、BMC Biotechnology、Heliyon等国际SCI期刊编委；担任《分析化学》、《材料导报》和《离子交换与吸附》等期刊青年编委。2022年获国家优秀青年科学基金资助。

代表性研究成果

1. Zhang, Peng; Zhu, Yaowei; Xiao, Chunsheng*; Chen, Xuesi*, Activatable Dual-functional Molecular Agents for Imaging-Guided Cancer Therapy. Advanced Drug Delivery Reviews 2023, 195, 114723.

2. Sun, Songjia; Wang, Dianwei; Yin, Renyong; Zhang, Peng; Jiang, Rihua*; Xiao, Chunsheng*, A Two-In-One Nanoprodrug for Photoacoustic Imaging-Guided Enhanced Sonodynamic Therapy. Small 2022, 18 (26), 2202558.

3. Wan Pengqi; Guo Wei; Wang Yongjie; Deng Mingxiao*; Xiao Chunsheng*; Chen Xuesi; Photosensitizer‐Polypeptide Conjugate for Effective Elimination of Candida albicans Biofilm. Advanced Healthcare Materials 2022, 11 (16), 2200268.

4. Ding, Xiaoya; Wang, Ye; Liu, Jiaying; Zhang, Peng; Li, Gao*; Sun, Tianmeng*; Xiao, Chunsheng*, Injectable In Situ Forming Double-Network Hydrogel to Enhance Transplanted Cell Viability and Retention. Chemistry of Materials 2021, 33 (15), 5885-5895.

5. Ding, Xiaoya.; Li, Gao.; Zhang, Peng.; Jin, E.; Xiao, Chunsheng*; Chen, Xuesi, Injectable Self-Healing Hydrogel Wound Dressing with Cysteine-Specific On-Demand Dissolution Property Based on Tandem Dynamic Covalent Bonds. Advanced Functional Materials 2021, 31 (19), 2011230.

6. Zhang, Peng; Zhang, Yu; Ding, Xiaoya; Shen, Wei; Li, Mingqian; Wagner, Ernst; Xiao, Chunsheng*; Chen, Xuesi*, A Multistage Cooperative Nanoplatform Enables Intracellular Co-Delivery of Proteins and Chemotherapeutics for Cancer Therapy. Advanced Materials 2020, 32 (46), 2000013.

7. Shen, Wei; Zhang, Yu; Wan, Pengqi; An, Lin; Zhang, Peng; Xiao, Chunsheng*; Chen, Xuesi*, Antineoplastic Drug-Free Anticancer Strategy Enabled by Host-Defense-Peptides-Mimicking Synthetic Polypeptides. Advanced Materials 2020, 32 (36), 2001108.

8. Ling Ling; Xiao Chunsheng*; Ma Yao; Jiang Liyan; Wang Sheng; Guo Limin; Jiang Shimei; Guo Xinhua*, 2-Phenyl-3-(p-aminophenyl) Acrylonitrile: A Reactive Matrix for Sensitive and Selective Analysis of Glycans by MALDI-MS. Analytical Chemistry 2019, 91 (14), 8801-8807.

9. Shen, Wei; He, Pan; Xiao, Chunsheng*; Chen, Xuesi*, From Antimicrobial Peptides to Antimicrobial Poly(α-amino acid)s. Advanced Healthcare Materials 2018, 7 (20), 1800354.

10. Shen, Wei; Liu, Wanguo; Yang, Huailin; Zhang, Peng; Xiao, Chunsheng*; Chen, Xuesi*, A Glutathione-responsive Sulfur Dioxide Polymer Prodrug as a Nanocarrier for Combating Drug-resistance in Cancer Chemotherapy. Biomaterials 2018, 178, 706-719.

课题组信息

课题组具有充足经费和科研场所，仪器设备齐全，为科学研究提供可靠保障。诚邀高分子、化学、药学、医学、材料及生物等相关专业学生加入。